The Nucleic Acid Scavenger Polyamidoamine Third-Generation Dendrimer Inhibits Fibroblast Activation and Granulation Tissue Contraction
نویسندگان
چکیده
منابع مشابه
Polyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue
BACKGROUND The potential nanocarrier polyamidoamine (PAMAM) generation 5 (G5-NH(2)) dendrimer has been shown to evoke lasting neuronal depolarization and cell death in a concentration-dependent manner. In this study we explored the early progression of G5-NH(2) action in brain tissue on neuronal and astroglial cells. RESULTS In order to describe early mechanisms of G5-NH(2) dendrimer action i...
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Introduction: Arsenic is known as a carcinogenic compound in drinking water. It can cause acute and chronic effects on human health. In this study, the effect of polyamidoamine dendrimer generation 3 (PAMAM G3) as adsorbents for removal of arsenic (V) from aqueous solutions was evaluated. Materials and Methods: Adsorption experiment was studied in batch system and the effect of different varia...
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BACKGROUND Polyamidoamine (PAMAM) and polypropylenimine (PPI) dendrimers are the commercially available and most widely used dendrimers in pharmaceutical sciences and biomedical engineering. In the present study, the loading and release behaviors of generation 3 PAMAM and generation 4 PPI dendrimers with the same amount of surface amine groups (32 per dendrimer) were compared using phenylbutazo...
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We report the first synthesis of a dendritic multicalixarene, featuring twenty-one calixarene units, which when adsorbed onto mica, forms regular assemblies which can then further aggregate to form larger clusters.
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UNLABELLED Mechanisms underlying the in vitro cytotoxicity of Polyamidoamine nano-dendrimers in human keratinocytes are explored. Previous studies demonstrated a systematic, dendrimer-generation-dependent cytotoxicity, oxidative stress, and genotoxicity. The emerging picture is of dendrimer endocytosis, endosomal rupture and subsequent mitochondrial attack and cell death. To understand the unde...
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ژورنال
عنوان ژورنال: Plastic and Reconstructive Surgery
سال: 2014
ISSN: 0032-1052
DOI: 10.1097/prs.0000000000000471